STUDY OF THE CONTENT OF POLYPHENOLS AND ANTIOXIDANT ACTIVITY OF THE EXTRACT OF GREEN MARINE ALGAE ULVA LACTUCA L.

It was studied the impact of a water-alcohol extract (70%) from marine green algae Ulva lactuca L., enriched with polyphenol fraction, and herbal preparation – Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) on indicators antioxidant protection liver blood plasma rats under acute stress (vertical fixation by dorsal neck fold). The total polyphenols flavonoids content in U. made 16.2±1.8 µg GAE/g 9.10±1.87 g QE/g, respectively, which 2 times higher than its amount 7.6±0.25 4.8±0.3 QE/g respectively. antiradical activity against ABTS+ alkyl-peroxyl radicals also almost compere Eleutherococcus. pharmacological effect phenolic complex Wistar manifested stabilization defense system. noted decrease malondialdehyde content, an increase level, reduced glutathione enzymes cycle rats. In terms efficiency, not inferior to reference Eleutherococcus, ability restore system, it superior that. lactuca, our opinion, is provided action constituent flavonoids, terpenoids, acids (hydroxybenzoic, hydroxycinnamic, coumaric, synapic), etc., have pronounced properties, prevents development lipid peroxidation oxidative stress. Thus, promising raw material for preparations that can potential endogenous system body at stress-induced disorders.